Coronavirus

Out of context: Reply #5934

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  • drgs3

    https://www.nature.com/articles/…
    https://www.nature.com/articles/…
    https://www.sciencedaily.com/rel…

    "A Neanderthal OAS1 isoform protects individuals of European ancestry against COVID-19 susceptibility and severity"

    There is a gene rs10774671-G which protects against Covid and other RNA-viruses like hepatitis c, which explains why some people get sick and others not so much, and more specifically why more black people get covid in America.

    15+/- years ago I bought a DNA testing kit from 23andme to check my Native American ancestry (it's 0%). They let you download your genome afterwards. I have this value:
    rsid chromosome position genotype
    rs10774671 12 111841576 AG

    GG would be optimal and AA offers no protection.

    Discuss

    • https://www.pnas.org…
      https://www.pnas.org…
      drgs
    • White power!palimpsest
    • But I thought race was a social constructBrabo_Brabo
    • The Duke of Edinburgh really did come back as a virus.Chimp
    • You native American now?pango
    • The ability to understand social constructs requires less chromosomes.palimpsest
    • According to 23andme I have "more Neanderthal DNA than 85% of other customers".drgs
    • The force is strong with this one.palimpsest
    • I'm pretty neanderthal also. Heavy set, thick skull. An arm dragger.Brabo_Brabo
    • haha, knuckle dragger. an arm drag is a wrestling move.Brabo_Brabo
    • Cave privilegeGnash
    • drgs, I have 83% more than most. What does this mean for us?misterhow
    • AG as wellmisterhow
    • Not having the G allele (AA) makes you 56% more likely to be hospitalized.drgs
    • Btw, I was wrong about the G allele in Africa, in fact its dominant there, it is the Neanderthal haplotype that is absent there.drgs
    • "The ancestral variant (rs10774671-G) is the major allele in African populations and became fixed in Neanderthal and Denisovan genomes...drgs
    • However, the ancestral variant, with its increased expression of the p46 isoform, was reintroduced into the European population via gene flow from Neanderthals"drgs
    • Covid mortality is low in Africa:
      https://www.healthda…
      drgs
    • But this confuses me:
      http://cdn.statcdn.c…
      drgs
    • Poverty and no access to healthcare plus Africans eat a healthier diet and get more exercise and clean air._niko
    • Vs their African American counterparts._niko
    • China also have your genome sequence. all those testing kits use chinese labs/resources. China aims to make a virus that Han chinese are immune from.shapesalad
    • ^My nightmaredrgs
    • Sounds like conspiracy talk. China has a lot of none Han Chinese as well. Unless their officials are highly uneducated, it seems unlikely.pango

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